To make the key decisions described in Section II, practitioners need to know the best-practice options that are available. This section provides more detailed information about design choices, organized according to topic. In addition to providing more technical information, it also discusses the implications of design choices for the system’s adherence to the Principles, particularly with regard to inclusivity, trustworthiness, data protection, and sustainability. Note that the order in which these topics are presented is not meant to imply a sequence or relative level of importance; each of these topics are interrelated and should be considered holistically.